Intracranial Hypertension

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Intracranial hypertension (IH) is a condition that is caused by increased cerebrospinal fluid (CSF) pressure within the skull. High CSF pressure can cause severe headaches and vision loss, which can result in blindness if not treated. There are two types of IH: primary and secondary. Primary IH, also known as idiopathic IH, commonly occurs in obese females around 20-45 years old, but the cause is unknown. Secondary IH is caused by specific drugs, sleep apnea and certain diseases including lupus and meningitis. The most standard therapy is the drug carbonic anhydrase inhibitors that suppress CSF production.

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