Osteogenesis Imperfecta

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Osteogenesis imperfecta (OI), also known as Brittle Bone Disease, is a lifelong disorder that affects the bones. It is characterized by a fragile skeleton, frequent broken bones, bone deformity and pain, short stature, spine curve, brittle teeth, loose joints and hearing loss in adulthood. OI is caused by a gene mutation that affects bone formation and strength, as well as the structure of other tissues. Treatment aims to support and decrease the number of fractures and disabilities. 

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