Alagille Syndrome

NewAlagille syndrome is a rare genetic disorder that affects various organ systems, primarily the liver and heart, throughout a person’s life. The signs and symptoms of Alagille syndrome can vary widely among individuals and may change over time. Effective management of Alagille syndrome requires a comprehensive, individualized approach due to the diverse range of symptoms [...]

NewAlagille syndrome (ALGS) is a complex genetic disorder that affects multiple systems in the body, including the liver, heart, kidneys, and skeleton. For those living with ALGS, the challenges can be profound and multifaceted, often significantly impacting their physical health, emotional well-being, and daily life. We’ve compiled a list of 10 considerations for those hoping [...]

NewFor people living with Alagille syndrome (ALGS), one challenging aspect that is often overlooked is the chronic itch and its impact on daily life. ALGS is a rare genetic disorder that affects various organ systems, primarily the heart and liver. When impaired liver function causes the build-up of excess bile in the body, patients may [...]

Life with Alagille syndrome (ALGS) presents unique challenges that extend beyond physical health. Whether you’re adjusting to a recent diagnosis or have been on this journey for a while, you may be confronted with the reality of the mental and emotional impact of this complex condition. Our goal is to help you understand and effectively [...]

It’s natural to feel uncertain or confused if you or someone you love is an older adult living with Alagille syndrome (ALGS). ALGS is a genetic condition that primarily affects the liver, heart, and kidneys, and it can present a unique set of challenges as a person ages. Managing this condition involves addressing symptoms during [...]

Seeking specialized health care for your child can be a stressful experience, especially if it’s for a rare condition like Alagille syndrome (ALGS). You probably have a lot of questions about life for your child with ALGS and depending on where you live, you may have to travel outside of your city or state to [...]

What is ALGS? Alagille syndrome (ALGS) is a rare genetic disorder affecting multiple parts of the body including the liver, heart, skeleton, eyes and kidneys. Symptoms are often detected early in childhood. When it affects the liver, it can lead to cholestatic pruritus which causes abnormalities and reduction of the liver’s bile ducts, according to [...]

Alagille syndrome (AGLS) with cholestatic pruritus is a rare genetic disorder caused by abnormalities in the liver’s bile ducts. It is a rare disease, with only between 3,000 and 30,000 cases in the United States, according to the National Institutes of Health. Structural abnormalities in the liver cause reduced flow of the digestive enzyme bile [...]

Itchy skin is never comfortable. But for people with cholestatic pruritus caused by Alagille syndrome (AGLS), it can be a constant, potentially distressing companion. Thankfully, there are some things to try, in addition to medications that a doctor may recommend, that could help relieve discomfort. AGLS is a genetic disorder that occurs when the liver [...]

Alagille syndrome (AGLS) is a genetic disorder of the liver that develops when bile ducts do not form properly or there are too few of them. Bile ducts are small tubes that allow bile, a digestive enzyme, to pass through to the small intestine. When bile cannot flow freely, it backs up into the liver, [...]