neuroscience

Hey Mighty fam 🌸

For many women, the days leading up to menstruation can feel like an emotional rollercoaster. Irritability, sadness, or even old memories resurfacing can catch even the most self-aware off guard. While these shifts are often chalked up to “hormones,” the reality is a fascinating interplay of brain chemistry, emotions, and psychology. Whether you’re a mental health professional or someone navigating these changes, understanding the science behind premenstrual emotional shifts can foster empathy and offer strategies for support. Here’s a look at what’s happening in the brain and body, and why these feelings matter.

Hormonal Changes and Brain Chemistry

The emotional fluctuations before menstruation are driven by shifts in estrogen and progesterone, hormones that influence key neurotransmitters like serotonin and dopamine. These neurotransmitters regulate mood, motivation, and emotional balance. Research shows that serotonin levels can drop by up to 30–40% during the luteal phase (the premenstrual period), contributing to irritability or low mood in about 20–40% of women with premenstrual syndrome (PMS) and 3–8% with premenstrual dysphoric disorder (PMDD) (Eriksson et al., 2008; American Psychiatric Association, 2013). Dopamine, linked to feelings of reward, also dips, which can make everything feel a bit heavier.

Why Old Memories Resurface

Ever notice how unresolved emotions or past experiences seem to bubble up before your period? This isn’t random. The amygdala, the brain’s emotional center, becomes more reactive when serotonin levels drop, while the hippocampus, responsible for memory, may pull up unresolved or traumatic memories. For women who’ve worked through therapy, these moments can feel frustrating, like revisiting emotions you thought were resolved. This is because hormonal changes temporarily reduce the brain’s ability to regulate emotions, making it harder to keep those feelings in check.

The Role of Emotional Regulation

The prefrontal cortex, which helps us make decisions and manage impulses, takes a hit during the premenstrual phase. Lower serotonin and dopamine levels impair its ability to “calm” emotional reactions, which is why even small triggers can feel overwhelming. For those with therapy experience, this can be a humbling reminder that biology doesn’t always bend to self-awareness. Still, understanding this process can help—knowing it’s your brain, not a personal failing, can make these moments easier to navigate.

A Deeper Perspective: Emotional Reflection

For some, these emotional shifts feel like more than just a biological quirk, they can be a chance for introspection. Many women, especially those who practice mindfulness, describe this time as an opportunity to revisit past experiences or emotions, almost like a monthly reset. While science doesn’t fully explain this, it’s possible that hormonal changes amplify emotional processing, allowing us to confront unresolved feelings. For others, particularly those without access to therapy or coping tools, these shifts can feel intense or even debilitating, especially in cases of PMDD.

Strategies for Navigating Emotional Shifts

Whether you’re a professional supporting clients or someone experiencing these changes, here are evidence-based ways to manage premenstrual emotional shifts:

• Mindfulness and Journaling: Practices like mindfulness meditation or writing can help process emotions and reduce reactivity.

• Cognitive-Behavioral Therapy (CBT): CBT can build skills to manage negative thoughts and emotional triggers (Yonkers et al., 2008).

• Lifestyle Adjustments: Regular exercise, sleep, and a balanced diet can stabilize mood by supporting neurotransmitter function.

• Medical Support: For severe symptoms like PMDD, consult a healthcare provider about options like selective serotonin reuptake inhibitors (SSRIs).

Premenstrual emotional shifts are more than “just hormones” they’re a complex dance of brain chemistry, psychology, and personal experience. By understanding how hormones affect serotonin, dopamine, and brain regions like the amygdala and prefrontal cortex, we can better support ourselves and others.

Whether you’re a clinician researching PMS/PMDD or someone seeking to understand your own cycle, recognizing these dynamics can empower you to approach these shifts with compassion and practical tools.

Key Takeaways: Hormonal fluctuations reduce serotonin and dopamine, driving emotional sensitivity in 20–40% of women (PMS) and 3–8% (PMDD).

The amygdala and hippocampus may trigger unresolved memories, even in those with therapy experience.Strategies like mindfulness, CBT, and lifestyle changes can help manage these emotional waves.

PMS isn’t just hormones, it’s your brain and heart navigating a complex cycle. From serotonin dips to resurfacing memories, these shifts affect 20–40% of women with PMS and 3–8% with PMDD. Whether you’re a clinician or riding these waves yourself, tools like mindfulness, CBT, or a chat with a doctor can help.

Let’s approach these moments with kindness and curiosity. I’d love to hear from you, what’s been your experience with premenstrual shifts?

#MentalHealt #WomensHealth #PMS #PMDD #emotionalWellbeing #neuroscience #MindBodyConnection

In November and December I was admitted to hospital when I lost control of my own body.
To begin with, the doctors and nurses at hospital and my gp told me it was anxiety.... Until I ended up in a wheelchair...

Double vision, paralysis, couldn't hear or speak, numbness.... I eventually felt like I was just 1 single eye on a hospital bed.

A scan showed inflammation on my brain stem.
Things went from bad to worse, it got to the point that I felt ready to give up. I told my mum "by tomorrow I won't be able to speak anymore, so if this is permanent, I'm not doing it"
I came face to face with the possibility that I was going to lose my life, or at least my life the way I knew it.

From being pushed in a wheelchair, to walking up hills in my favourite rural spot, in just over a month, seems like a miracle, my life was handed back to me.
There's still a long road to full recovery and I'm not safe yet.

But I'm so thankful to the doctors and nurses who helped me.
In a strange way, I feel as though I've been given the chance to live with a new perspective.

And with this new outlook on life, I'm not looking back.

#brainhealth #brainstem #neuroscience #neuro #live #Life #itsnotanxiety #bepersistant