Epilepsy

Please be patient with ADHD people as they may take longer processing some information, this is also why they deal with overwhelm.

(Image Source Autism -Synaptic Pruning Deficits. On the left you will see a neurotypical synaptic pruning and on the right an ADHD neurodivergent shows less neuron synaptic pruning.)

A Beautiful Unpruned Mind

The human brain is an intricate network of neurons, which communicate through synapses—tiny bridges that allow electrical and chemical signals to pass between cells. During early development, an overabundance of synapses is formed, creating vast neural pathways. However, as we grow, a process known as synaptic pruning takes place. This natural refinement removes unnecessary connections, streamlining brain function and enhancing efficiency (Abitz et al., 2007).

Yet, for some individuals, this pruning process doesn’t occur as extensively as in neurotypical brains. One such group is the neurodiverse or autistic individuals, whose brains retain a higher density of synapses (Tang et al., 2014). While this divergence in neural architecture contributes to characteristic autistic traits, it can also be the foundation for extraordinary cognitive abilities, often linked to savant syndrome.

Synaptic Pruning: The Brain’s Gardener

In infancy and early childhood, the brain experiences a surge in synapse formation, creating a dense web of neural connections. As a child matures, the brain refines itself by eliminating less-used pathways, enhancing efficiency and specialization. Research suggests that by adulthood, neurotypical individuals may have 41% fewer neurons than at birth (Abitz et al., 2007).

However, in autistic brains, this pruning is significantly reduced. Studies indicate that by late childhood, synaptic density decreases by only about 16%, compared to roughly 50% in neurotypical individuals (Tang et al., 2014). This preservation of synapses means that autistic individuals often have heightened connectivity in certain brain regions, which can lead to both challenges and unique cognitive strengths.

The Link Between Autism and Savant Abilities

A fascinating consequence of reduced synaptic pruning is the increased likelihood of savant abilities—exceptional skills in areas such as mathematics, music, or memory. While only about 1% of the general population exhibits savant-like traits, approximately 10% of autistic individuals display such abilities, with some estimates suggesting an even higher prevalence (Treffert, 2009).

One explanation lies in the brain’s hemispheric compensation. Research suggests that damage or developmental differences in the left hemisphere, often observed in autistic individuals, may lead to right hemisphere dominance, which is associated with heightened pattern recognition, spatial awareness, and artistic or mathematical talents (Hughes, 2012). Additionally, brain-derived neurotrophic factor (BDNF) plays a role in neuroplasticity and synaptic growth, potentially fostering enhanced neural connections in those with savant abilities (Schenk et al., 2012).

A Different Kind of Intelligence

While autism presents challenges in areas like social communication, it also offers unique cognitive strengths. A mind that retains more connections may have increased access to vast amounts of raw data, leading to exceptional memory, pattern recognition, and problem-solving abilities (Hughes, 2012). Some researchers speculate that this neural wiring may enable individuals to process information in ways that are unavailable to the neurotypical brain.

The Beauty of an Unpruned Mind

The way our brains develop shapes not only how we think but also who we are. While synaptic pruning streamlines efficiency in most individuals, a brain that holds onto its extra connections may unlock abilities beyond the ordinary. Rather than seeing this as a deficit, it may be more fitting to view it as an alternative form of intelligence—one that fosters unique perspectives, remarkable skills, and in some cases, savant-level genius.

by

Carlita Shaw

#adhd, #neurodivergent #neurodiverse #women #WomenWithADHD #Anxiety #Midlifecrisis #BrainInjury #PTSD #burnout

References

Abitz, M., Damgaard, M., Maier, N., Sakata, M., Aida, T., Kawakami, R., … & Pakkenberg, B. (2007). Excess of neurons in the human newborn mediodorsal thalamus compared with that of the adult. Cerebral Cortex, 17(11), 2573-2580. pubmed.ncbi.nlm.nih.gov/17218480

Hughes, J. R. (2012). A review of Savant Syndrome and its possible relationship to epilepsy. Epilepsy & Behavior, 23(4), 288-294.

Schenk, F., Eckert, P., & Hunziker, J. (2012). Brain-derived neurotrophic factor (BDNF) and its role in neuroplasticity. Frontiers in Neuroscience, 6, 12.

Tang, G., Gudsnuk, K., Kuo, S. H., Cotrina, M. L., Rosoklija, G., Sosunov, A., Sonders, M. S., Kanter, E., Castagna, C., Yamamoto, A., Arancio, O., Peterson, B. S., Champagne, F., Dwork, A. J., Goldman, J., & Yue, Z. (2014). Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron, 83(5), 1131-1143. doi.org/10.1016/j.neuron.2014.07.040

Treffert, D. A. (2009). The savant syndrome: An extraordinary condition. Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1522), 1351-1357Website- Synaptic growth, synesthesia & savant abilities | Embrace Autism

Additional Notes on the Study

Tang, G., and Sonders, M. S. (2014) contributed to a study that explored the relationship between developmental dendritic pruning, elevated mTORC1 signaling, macroautophagy, and autism spectrum disorder (ASD). The study, conducted at Columbia University Medical Center (CUMC), found that loss of mTOR-dependent macroautophagy leads to autistic-like synaptic pruning deficits, characterized by increased dendritic spine density and reduced developmental spine pruning in layer V pyramidal neurons in postmortem ASD temporal lobe

The study by Tang et al. (2014) was supported by the Simons Foundation, the U.S. Department of Defense (TS110056), the Parkinson’s Disease Foundation, the JPB Foundation, and the National Institutes of Health (NIH K01MH096956, R01MH64168, DP2OD001674, R01NS049442). Additional funding came from the American Heart Association, and brain tissue samples were provided by the Harvard Brain Bank and the Maryland NICHD Brain & Tissue Bank

(You can find this article with an explainer video, in my blog lifepathfrequencies over on WordPress)

🙌 Yes!!

Yep, I am Also your confidence booster!
&
Your cheerleader ( 📣 🙃🤭🙌🙌 another fun fact about me - I was the first freshman in my high school to make the Varsity football cheerleading squad And I Also was a cheerleading coach in high school for junior high school kids And I did all of that while also teaching dance and helping to run a dance school in high school too, while also continuing my own dance training daily because my first love since the age of 3 has always been the beautiful art of dance- or like one of my all time favorite Professional dance companies that I paid to see live in NYC was called- “Shaping Sound”.

Yeah, I Really miss those days of Energy.

These days, if I have any energy or let’s say the infrequent but still a huge gift of having more than a little energy, it’s funny in that I can recognize the immense difference in a blink of an eye.

Oh, yeah, and about the badass part of this quote image 👆
Not having energy and still doing all that I do, That is what makes me Badass, is how I look at it- after straightening out my Perspective and Reframing my Headspace.
And honestly without my onset of major depressive disorder at age 34 (I am now 52), I would never have really achieved Becoming Badass! And, I always admired Badass people of all kinds.

Always remember this whole hard thing called life and life transitions requires us to take on new, healthier Perspectives Always, And this is what I learned from the Headspace app is also called “Reframing” (best app in the world, at least when I used it daily in 2017 - 2019)

And I have specific, Large, photo album folders on my phone - 1 titled “Reframing Headspace” from my saved key takeaways from each Headspace course lesson I took (that Of Course I will be sharing with you in my group Resilience and Mindfulness) and I have another specific, Large, photo album folder titled “Perspectives” that Of Course I will be sharing with you in my group titled Resilience and Mindfulness)

To anyone seeing this post outside of my group - here is the direct link Resilience and Mindfulness and Join Us for So Much & because literally Everyone needs to learn both Resilience and Mindfulness (and, I don’t stop there with what goodies I share To Help YOU 😁🙃)

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